Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4761397 | 0.88 | CYP1A2 (0.38) | — | |
| Hydrochloric Acid SCHEMBL3151086 | 0.87 | CYP1A2 (0.38) | — | |
| SCHEMBL3145939 | 0.85 | CYP1A2 (0.38) | — | |
| SCHEMBL3155310 | 0.84 | ABL1 (0.41) | — | |
| SCHEMBL3145803 | 0.84 | DDT (0.39) | — | |
| Hydrochloric Acid SCHEMBL3780667 | 0.84 | GABRG2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL3767934 | 0.83 | DDT (0.38) | — | |
| SCHEMBL3145932 | 0.82 | CHRNB4 (0.39) | CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3150823 | 0.82 | FYN (0.41) | KDM1A | |
| SCHEMBL3141373 | 0.82 | KDM1A (0.36) | KDM1ACHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-A1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007085750-A1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2007-08-02 | — | — | WO | disclosed |