Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 9/20 | 0.43 |
| ▸ | VCP | P55072 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MITF | O75030 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461799 | 1.00 | MEN1 (0.52) | MEN1PSMD14KMT2AL3MBTL1FBP1 | |
| SCHEMBL18590415 | 0.95 | MEN1 (0.54) | MEN1PSMD14KMT2AL3MBTL1FBP1 | |
| SCHEMBL145009 | 0.87 | VCP (0.49) | MEN1PSMD14KMT2AL3MBTL1FBP1 | |
| SCHEMBL121200 | 0.87 | VCP (0.49) | MEN1PSMD14KMT2AL3MBTL1FBP1 | |
| SCHEMBL16831526 | 0.81 | VCP (0.50) | MEN1PSMD14KMT2AL3MBTL1FBP1 | |
| SCHEMBL16831527 | 0.81 | VCP (0.50) | MEN1PSMD14KMT2AL3MBTL1FBP1 | |
| SCHEMBL19995519 | 0.79 | VCP (0.58) | MEN1PSMD14KMT2AL3MBTL1FBP1 | |
| SCHEMBL19995518 | 0.79 | VCP (0.58) | MEN1PSMD14KMT2AL3MBTL1FBP1 | |
| SCHEMBL458238 | 0.77 | FBP1 (0.53) | MEN1PSMD14KMT2AL3MBTL1FBP1 | |
| SCHEMBL458434 | 0.77 | FBP1 (0.53) | MEN1PSMD14KMT2AL3MBTL1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |