Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611680 | 1.00 | KCNA5 (0.45) | KCNA5RAB9APOLBALDH1A1GRM5 | |
| SCHEMBL18416421 | 0.79 | HDAC3 (0.47) | KCNA5RAB9APOLBALDH1A1GRM5 | |
| SCHEMBL18421162 | 0.79 | HDAC3 (0.47) | KCNA5RAB9APOLBALDH1A1GRM5 | |
| SCHEMBL4631647 | 0.78 | KCNA5 (0.49) | KCNA5ALDH1A1GRM5CYP3A4CYP2C19 | |
| SCHEMBL12068487 | 0.78 | ALDH1A1 (0.50) | KCNA5ALDH1A1GRM5CYP3A4CYP2C19 | |
| SCHEMBL5029175 | 0.78 | KCNA5 (0.49) | KCNA5POLBALDH1A1GRM5CYP3A4 | |
| SCHEMBL1516145 | 0.78 | ALDH1A1 (0.50) | KCNA5ALDH1A1GRM5CYP3A4CYP2C19 | |
| SCHEMBL29078127 | 0.78 | KCNA5 (0.49) | KCNA5ALDH1A1GRM5CYP3A4CYP2C19 | |
| SCHEMBL14777447 | 0.77 | KCNA5 (0.47) | KCNA5ALDH1A1GRM5CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL68317 | 0.77 | ALDH1A1 (0.53) | KCNA5ALDH1A1GRM5CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923544-B1 | METHOD FOR THE SYNTHESIS OF AMINES AND AMINO ACIDS WITH ORGANOBORON DERIVATIVES | UNIV SOUTHERN CALIFORNIA (US) | 2008-10-15 | — | — | EP | disclosed |
| US-6232467-B1 | BIOSYNTHESIS OF AN AMINE WITH KETONE AND BORON COMPOUND; COMPOUNDLIBRARIES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2001-05-15 | — | — | US | disclosed |
| EP-0923544-A4 | METHOD FOR THE SYNTHESIS OF AMINES AND AMINO ACIDS WITH ORGANOBORON DERIVATIVES | UNIV SOUTHERN CALIFORNIA (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0923544-A1 | METHOD FOR THE SYNTHESIS OF AMINES AND AMINO ACIDS WITH ORGANOBORON DERIVATIVES | University of Southern California (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998000398-A1 | METHOD FOR THE SYNTHESIS OF AMINES AND AMINO ACIDS WITH ORGANOBORON DERIVATIVES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1998-01-08 | — | — | WO | disclosed |