Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611120 | 0.89 | KDM4E (0.49) | KDM4EGAA | |
| SCHEMBL4164330 | 0.89 | KDM4E (0.58) | KDM4EGAA | |
| SCHEMBL4164304 | 0.85 | KDM4E (0.55) | KDM4EGAA | |
| SCHEMBL4169559 | 0.85 | SIGMAR1 (0.67) | KDM4EALDH1A1ALOX15SIGMAR1 | |
| Bromide SCHEMBL4173363 | 0.84 | KDM4E (0.53) | KDM4EGAA | |
| Bromide SCHEMBL4174825 | 0.83 | SIGMAR1 (0.65) | KDM4EALDH1A1ALOX15SIGMAR1 | |
| SCHEMBL4168265 | 0.79 | SLC6A3 (0.59) | SIGMAR1 | |
| Bromide SCHEMBL4171916 | 0.78 | SLC6A3 (0.58) | SIGMAR1 | |
| SCHEMBL4474652 | 0.78 | KDM4E (0.74) | KDM4EALDH1A1GAA | |
| SCHEMBL11721357 | 0.74 | GAA (0.56) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981849-A1 | HETEROCYCLIC COMPOUNDS | LEK Pharmaceuticals D.D. (SI) | 2008-10-22 | — | — | EP | claimed |
| WO-2007073935-A1 | HETEROCYCLIC COMPOUNDS | LEK PHARMACEUTICALS D.D. (SI) | 2007-07-05 | — | — | WO | claimed |