SCHEMBL4612232

SCHEMBL4612232

CCC(C)(C)OOC(=O)c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.49
ALDH1A1 P00352 5/20 0.49
TSHR P16473 2/20 0.49
HSD17B10 Q99714 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
AKR1C3 P42330 2/20 0.46
CYP1A2 P05177 2/20 0.45
CYP2C19 P33261 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
LMNA P02545 1/20 0.43
CYP2D6 P10635 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6708934 0.90 ALDH1A1 (0.54) ELANEALDH1A1TSHRHSD17B10TDP1
SCHEMBL2030231 0.89 TSHR (0.50) ELANEALDH1A1TSHRHSD17B10TDP1
SCHEMBL7907952 0.89 ALDH1A1 (0.46) ELANEALDH1A1TSHRHSD17B10TDP1
SCHEMBL7905008 0.87 ALDH1A1 (0.47) ELANEALDH1A1TSHRHSD17B10TDP1
SCHEMBL7905010 0.85 TSHR (0.44) ELANEALDH1A1TSHRHSD17B10TDP1
SCHEMBL2528251 0.85 ALDH1A1 (0.43) ELANEALDH1A1TSHRHSD17B10TDP1
SCHEMBL29388336 0.84 ALDH1A1 (0.69) ELANEALDH1A1TSHRHSD17B10TDP1
SCHEMBL1815675 0.84 ALDH1A1 (0.69) ELANEALDH1A1TSHRHSD17B10TDP1
SCHEMBL25264 0.84 TDP1 (0.68) ELANEALDH1A1TSHRHSD17B10TDP1
SCHEMBL6162550 0.83 TSHR (0.44) ELANEALDH1A1TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0520364-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1997-09-17 EP claimed
CN-117836390-A Liquid crystal composition and liquid crystal element 九州奈米技术光学股份有限公司 2024-04-05 CN disclosed
CN-111065691-B Dye compound having polymerizable group and polymer containing the same as monomer unit 柯尼卡美能达株式会社 2022-05-03 CN disclosed
CN-107203063-B Substrate for display element, method for manufacturing substrate for display element, and display element JSR株式会社 2022-04-05 CN disclosed
CN-106462011-B Liquid crystal display element, liquid crystal alignment film, and liquid crystal alignment treatment agent 日产化学工业株式会社 2021-11-12 CN disclosed
CN-109642140-B Photosensitive adhesive composition 日产化学株式会社 2021-08-31 CN disclosed
CN-109563194-B Imprint material 日产化学株式会社 2021-06-22 CN disclosed
CN-108139673-B Metal oxide containing materials, methods of making and methods of using the same 默克专利有限公司 2021-06-15 CN disclosed
CN-112639618-A Negative photosensitive resin composition 日产化学株式会社 2021-04-09 CN disclosed
CN-107077024-B Liquid crystal display element 日产化学工业株式会社 2020-11-17 CN disclosed
CN-107003570-B Liquid crystal display element 日产化学工业株式会社 2020-10-09 CN disclosed
CN-107003571-B Liquid crystal display element 日产化学工业株式会社 2020-10-09 CN disclosed
CN-111566144-A Resin composition for insulating film 日产化学株式会社 2020-08-21 CN disclosed
CN-111065691-A Dye compound having polymerizable group and polymer containing the same as monomer unit 柯尼卡美能达株式会社 2020-04-24 CN disclosed
CN-108698427-B Cylindrical printing plate, cylindrical printing plate precursor, and method for producing same 富士胶片株式会社 2020-01-14 CN disclosed
EP-1471387-B1 Photosensitive composition and compound used thereof FUJIFILM CORP (JP) 2015-11-11 EP disclosed
EP-1449651-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2008-10-29 EP disclosed
EP-1096314-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-05-02 EP disclosed