Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030231 | 0.93 | TSHR (0.50) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL9103099 | 0.86 | TSHR (0.43) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL27458878 | 0.84 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL22773852 | 0.84 | ADRB2 (0.45) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL4612232 | 0.83 | ELANE (0.49) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL2439254 | 0.83 | TSHR (0.59) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL27927289 | 0.83 | ALDH1A1 (0.57) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL29416841 | 0.82 | TDP1 (0.49) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL31540149 | 0.82 | TDP1 (0.49) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 | |
| SCHEMBL31540148 | 0.82 | TDP1 (0.49) | TSHRALDH1A1TDP1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589051-A1 | Process for preparing graft polyols using enol ethers as reaction moderators | BASF Corporation (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1192198-A1 | PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR | BASF CORPORATION (US) | 2002-04-03 | — | — | EP | disclosed |
| US-6172164-B1 | POLYMERIZING AN ETHYLENICALLY UNSATURATED MONOMER WITH A MACROMER WITH UNSATURATION IN PRESENCE OF FREE RADICAL INITIATOR BLEND OF TERT-AMYL PEROXY (2-ETHYLHEXANOATE AND 1,1'BIS(TERT-AMYL PEROXY) CYCLOHEXANE | BASF CORPORATION | 2001-01-09 | — | — | US | disclosed |
| WO-2000059971-A1 | PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR | BASF CORPORATION (DE) | 2000-10-12 | — | — | WO | disclosed |