Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612286 | 0.88 | ALDH1A1 (0.32) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL9577911 | 0.79 | CA2 (0.32) | CHRM1ADRA1AALDH1A1 | |
| SCHEMBL9574574 | 0.77 | CHRM1 (0.31) | CHRM1ADRA1A | |
| SCHEMBL4611947 | 0.77 | CA1 (0.33) | — | |
| SCHEMBL4585507 | 0.73 | HMGCR (0.48) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL52090 | 0.72 | ALDH1A1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL19283792 | 0.71 | CPA1 (0.35) | HIF1A | |
| SCHEMBL23495469 | 0.70 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL16632929 | 0.70 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL28479123 | 0.70 | ALDH1A1 (0.33) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238962-B1 | A process for the preparation of michael-adducts | FIRMENICH & CIE (CH) | 2008-02-27 | — | — | EP | claimed |