SCHEMBL461258

SCHEMBL461258

CCn1nccc1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28960760 0.98
Hydrochloric Acid SCHEMBL1359153 0.98
SCHEMBL23400943 0.84
SCHEMBL13212232 0.80 SLC9A1 (0.41)
SCHEMBL11499176 0.79 SLC9A1 (0.42)
SCHEMBL4975596 0.78 ALDH1A1 (0.33)
SCHEMBL859734 0.77
SCHEMBL31287918 0.77 SLC9A1 (0.44)
SCHEMBL256684 0.76
SCHEMBL27431987 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4669612-B2 2011-04-13 JP claimed
US-20030109717-A1 Preparation of substituted hydroxypyrazoles GOTZ NORBERT (DE) 2003-06-12 US claimed
JP-2002529454-A 2002-09-10 JP claimed
EP-1127050-A1 METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 2001-08-29 EP claimed
WO-2000027821-A1 METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO claimed
US-5808092-A CYCLIZATION REACTION OF ALKYL 3-ALKOXYACRYLATE WITH ETHYLHYDRAZINE; BY-PRODUCT INHIBITION UBE INDUSTRIES, LTD. (JP) 1998-09-15 US claimed
CN-1189161-A Herbicidal ketals and spirocycles DU PONT (US) 1998-07-29 CN claimed
EP-0837058-A1 Process for preparing 1-ethyl-5-hydroxypyrazole UBE INDUSTRIES, LTD. (JP) 1998-04-22 EP claimed
JP-9291088-A None JP disclosed
EP-4658662-A1 MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS Yuhan Corporation (KR) 2025-12-10 EP disclosed
US-20250353864-A1 INDAZOLE CONTAINING MACROCYCLES AND THEIR USE BLOSSOMHILL THERAPEUTICS INC (US) 2025-11-20 US disclosed
EP-4119545-B1 PYRAZOLE CARBOXYLATE COMPOUND AND USE THEREOF SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) 2025-11-12 EP disclosed
WO-2025202003-A1 POLYMERISATION INHIBITORS BASF SE (DE) 2025-10-02 WO disclosed
EP-4536224-A1 INDAZOLE CONTAINING MACROCYCLES AND THEIR USE Blossomhill Therapeutics, Inc. (US) 2025-04-16 EP disclosed
EP-0344775-A1 Process for producing 4-benzoyl-5-hydroxypyrazoles NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-12-06 EP disclosed
US-4885022-A Herbicidal pyrazole derivatives NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-12-05 US disclosed
CN-88101455-A Pyrazole derivatives and herbicides containing the same 1988-09-28 CN disclosed
EP-0282944-A2 Pyrazole derivative and herbicide containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1988-09-21 EP disclosed
US-4744815-A 4-benzoyl-1-alkyl (alkenyl) - pyrazoles, composition containing them, herbicidal method of using them, and intermediate in their preparation NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1988-05-17 US disclosed
EP-0203428-A1 Herbicidal 4-benzoyl-1-alkyl(alkenyl)-pyrazoles NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1986-12-03 EP disclosed