SCHEMBL4612602

SCHEMBL4612602

Ic1cc2ccc3ncccc3c2nc1I

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.56
CYP3A4 P08684 2/20 0.49
KDM4E B2RXH2 4/20 0.48
MAPT P10636 4/20 0.48
ALDH1A1 P00352 7/20 0.40
HTT P42858 5/20 0.40
MEN1 O00255 4/20 0.40
HSP90AA1 P07900 4/20 0.40
KMT2A Q03164 4/20 0.40
HIF1A Q16665 3/20 0.40
TP53 P04637 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
USP2 O75604 2/20 0.40
HPGD P15428 2/20 0.40
ALOX15 P16050 2/20 0.40
SLC6A2 P23975 2/20 0.40
MAPK1 P28482 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
HSD17B10 Q99714 2/20 0.40
EGFR P00533 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28056196 0.77 CCR1 (0.59) LMNACYP3A4KDM4EMAPTALDH1A1
SCHEMBL4613312 0.77 LMNA (0.67) LMNACYP3A4KDM4EMAPTALDH1A1
SCHEMBL28431094 0.76 LMNA (0.65) LMNACYP3A4KDM4EMAPTALDH1A1
SCHEMBL7645550 0.73 LMNA (0.56) LMNACYP3A4KDM4EMAPTALDH1A1
SCHEMBL28941839 0.73 LMNA (0.56) LMNACYP3A4KDM4EMAPTALDH1A1
SCHEMBL462223 0.73 LMNA (0.56) LMNACYP3A4KDM4EMAPTALDH1A1
SCHEMBL3262312 0.73 LMNA (0.56) LMNACYP3A4KDM4EMAPTALDH1A1
SCHEMBL873855 0.73 LMNA (0.56) LMNACYP3A4KDM4EMAPTALDH1A1
SCHEMBL8313 0.72 LMNA (1.00) LMNACYP3A4KDM4EMAPTALDH1A1
SCHEMBL6513577 0.72 LMNA (1.00) LMNACYP3A4KDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1520846-B1 Method for producing polymerized hydrocarbon JFE CHEMICAL CORP (JP) 2008-03-05 EP disclosed
US-7138484-B2 Method for producing polymerized hydrocarbon JFE CHEMICAL CORPORATION (JP) 2006-11-21 US disclosed
US-20050075478-A1 Method for producing polymerized hydrocarbon JFE CHEMICAL CORPORATION (JP) 2005-04-07 US disclosed
EP-1520846-A1 Method for producing polymerized hydrocarbon JFE Chemical Corporation (JP) 2005-04-06 EP disclosed