SCHEMBL4612758

SCHEMBL4612758

c1csc(C2=NOCCS2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RPS6KB2 Q9UBS0 3/20 0.38
KDM4E B2RXH2 5/20 0.37
ALDH1A1 P00352 5/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
MAPT P10636 3/20 0.37
HPGD P15428 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
HSD17B10 Q99714 4/20 0.36
NISCH Q9Y2I1 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
CYP3A4 P08684 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2E1 P05181 1/20 0.34
CYP2A6 P11509 1/20 0.34
CYP2B6 P20813 1/20 0.34
TDO2 P48775 1/20 0.34
HTR2C P28335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2785438 0.72 NISCH (0.46) RPS6KB2KDM4EALDH1A1MEN1KMT2A
SCHEMBL10750163 0.70 MAPT (0.37) KDM4EMAPTNPC1RAB9ACYP3A4
SCHEMBL21664153 0.69 NISCH (0.43) RPS6KB2KDM4EALDH1A1MEN1KMT2A
SCHEMBL7596918 0.68 HTR2C (0.41) RPS6KB2KDM4EALDH1A1MEN1KMT2A
SCHEMBL7921123 0.66 CHRM2 (0.38) KDM4EALDH1A1MAPTHPGDHSD17B10
Fluoride SCHEMBL491501 0.66 L3MBTL1 (0.55) RPS6KB2KDM4EALDH1A1MEN1KMT2A
SCHEMBL2320946 0.65 RPS6KB2 (0.36) RPS6KB2KDM4EALDH1A1MEN1KMT2A
SCHEMBL7135870 0.63 MAPT (0.52) RPS6KB2KDM4EALDH1A1MEN1KMT2A
SCHEMBL29839941 0.63 MAPT (0.45) RPS6KB2KDM4EALDH1A1MEN1KMT2A
SCHEMBL3545 0.63 L3MBTL1 (0.57) RPS6KB2KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2352876-B1 TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS BASF SE (DE) 2012-12-12 EP claimed
EP-1135239-B1 WOOD PRESERVATIVE FORMULATIONS HICKSON INTERNAT PLC (GB) 2008-02-06 EP claimed
US-20060160791-A1 Wood preservative formulations WILLIAMS GARETH 2006-07-20 US claimed
US-5922113-A NOVEL COMPOUNDS FOR USE IN PAINTS, LACQUERS, WHITEWASHES AND VARNISHES; FOR EXAMPLE 5,6-DIHYDRO-3-(2-THIENYL)-1,4,2-OXATHIAZINE, 4-OXIDE JANSSEN PHARMACEUTICA, N.V. (BE) 1999-07-13 US claimed
EP-0715495-B1 ANTIBACTERIAL AND ANTIFOULING OXATHIAZINES AND THEIR OXIDES JANSSEN PHARMACEUTICA NV (BE) 1998-03-11 EP claimed
US-5712275-A ESPECIALLY FOR UNDERWATER STRUCTURES, USE IN A MARINE ENVIRONMENT JANSSEN PHARMACEUTICA, N.V. (BE) 1998-01-27 US claimed
EP-0715495-A1 ANTIBACTERIAL AND ANTIFOULING OXATHIAZINES AND THEIR OXIDES JANSSEN PHARMACEUTICA N.V. (BE) 1996-06-12 EP claimed
WO-1995005739-A1 ANTIBACTERIAL AND ANTIFOULING OXATHIAZINES AND THEIR OXIDES JANSSEN PHARMACEUTICA N.V. (BE) 1995-03-02 WO claimed
EP-1135239-B1 WOOD PRESERVATIVE FORMULATIONS HICKSON INTERNAT PLC (GB) 2008-02-06 EP disclosed
US-20060160791-A1 Wood preservative formulations WILLIAMS GARETH 2006-07-20 US disclosed
EP-1135239-A1 WOOD PRESERVATIVE FORMULATIONS HICKSON INTERNATIONAL PLC (GB) 2001-09-26 EP disclosed
WO-2000032371-A1 WOOD PRESERVATIVE FORMULATIONS HICKSON INTERNATIONAL PLC (GB) 2000-06-08 WO disclosed
US-5922113-A NOVEL COMPOUNDS FOR USE IN PAINTS, LACQUERS, WHITEWASHES AND VARNISHES; FOR EXAMPLE 5,6-DIHYDRO-3-(2-THIENYL)-1,4,2-OXATHIAZINE, 4-OXIDE JANSSEN PHARMACEUTICA, N.V. (BE) 1999-07-13 US disclosed
EP-0715495-B1 ANTIBACTERIAL AND ANTIFOULING OXATHIAZINES AND THEIR OXIDES JANSSEN PHARMACEUTICA NV (BE) 1998-03-11 EP disclosed
US-5712275-A ESPECIALLY FOR UNDERWATER STRUCTURES, USE IN A MARINE ENVIRONMENT JANSSEN PHARMACEUTICA, N.V. (BE) 1998-01-27 US disclosed
EP-0715495-A1 ANTIBACTERIAL AND ANTIFOULING OXATHIAZINES AND THEIR OXIDES JANSSEN PHARMACEUTICA N.V. (BE) 1996-06-12 EP disclosed
WO-1995005739-A1 ANTIBACTERIAL AND ANTIFOULING OXATHIAZINES AND THEIR OXIDES JANSSEN PHARMACEUTICA N.V. (BE) 1995-03-02 WO disclosed
US-4675044-A DEFOLIANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 1987-06-23 US disclosed
US-4569690-A HERBICIDES, FUNGICIDES, PLANT DESSICANTS, DEFOLIANTS UNIROYAL, INC. (US) 1986-02-11 US disclosed
EP-0104940-A1 3-Aryl-5,6-dihydro-1,4,2-oxathiazines and their oxides UNIROYAL, INC. (US) 1984-04-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060160791-A1 Wood preservative formulations ATL3, WIZ, NNT RPS6KB2 4527/4885KDM4E 1254/4885ALDH1A1 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.