Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | CDC25B | P30305 | 3/20 | 0.36 |
| ▸ | ACP1 | P24666 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943455 | 0.74 | SIRT2 (0.52) | SIRT2PTPN1CDC25BACP1GAA | |
| SCHEMBL8943241 | 0.74 | SIRT2 (0.52) | SIRT2PTPN1CDC25BACP1GAA | |
| SCHEMBL21961902 | 0.72 | SIRT2 (0.45) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL17696764 | 0.72 | SIRT2 (0.45) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL11487039 | 0.71 | STS (0.41) | PTPN1 | |
| SCHEMBL21961906 | 0.70 | SIRT2 (0.42) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL15526485 | 0.68 | SIRT2 (0.53) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL663852 | 0.68 | SIRT2 (0.53) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL112728 | 0.68 | SIRT2 (0.53) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL10186569 | 0.68 | SIRT2 (0.53) | SIRT2PTPN1CDC25BACP1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055654-B1 | PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS | DAICEL CHEM (JP) | 2008-02-20 | — | — | EP | disclosed |
| US-7183423-B1 | Process for the preparation of organic compounds with imide catalysts | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1055654-A1 | PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS | Daicel Chemical Industries, Ltd. (JP) | 2000-11-29 | — | — | EP | disclosed |