Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.39 |
| ▸ | ACP1 | P24666 | 4/20 | 0.39 |
| ▸ | CDC25B | P30305 | 4/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17696764 | 1.00 | SIRT2 (0.45) | SIRT2PTPN1ACP1CDC25BCPT1A | |
| SCHEMBL21961906 | 0.98 | SIRT2 (0.42) | SIRT2PTPN1ACP1CDC25BCPT1A | |
| SCHEMBL21961910 | 0.83 | — | — | |
| SCHEMBL10186569 | 0.79 | SIRT2 (0.53) | SIRT2PTPN1ACP1CDC25BPRKCA | |
| SCHEMBL3659625 | 0.79 | SIRT2 (0.53) | SIRT2PTPN1ACP1CDC25BPRKCA | |
| SCHEMBL15526485 | 0.79 | SIRT2 (0.53) | SIRT2PTPN1ACP1CDC25BPRKCA | |
| SCHEMBL663852 | 0.79 | SIRT2 (0.53) | SIRT2PTPN1ACP1CDC25BPRKCA | |
| SCHEMBL112728 | 0.79 | SIRT2 (0.53) | SIRT2PTPN1ACP1CDC25BPRKCA | |
| SCHEMBL10186571 | 0.79 | SIRT2 (0.53) | SIRT2PTPN1ACP1CDC25BPRKCA | |
| SCHEMBL17307358 | 0.78 | MAPT (0.36) | SIRT2PTPN1ACP1CDC25BCPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403445-A1 | SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES | CORNELL UNIVERSITY | 2021-12-30 | — | — | US | disclosed |
| WO-2020102816-A1 | SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES | CORNELL UNIVERSITY (US) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403445-A1 | SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES | LTC4S, LSS, CYCS | SIRT2 862/4885PTPN1 4008/4885ACP1 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.