SCHEMBL461365

SCHEMBL461365

CCCCOC(=O)NCC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.58
EPHX2 P34913 2/20 0.51
EPHX1 P07099 1/20 0.50
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2185194 0.98 ACHE (0.56) ACHEEPHX2EPHX1ALDH1A1
SCHEMBL8849277 0.94 ACHE (0.61) ACHEEPHX2EPHX1
SCHEMBL4751426 0.93 ACHE (0.51) ACHEEPHX2EPHX1ALDH1A1
SCHEMBL8576882 0.92 ACHE (0.65) ACHEEPHX2EPHX1
SCHEMBL9444232 0.92 ACHE (0.65) ACHEEPHX2EPHX1
SCHEMBL8913848 0.92 ACHE (0.65) ACHEEPHX2EPHX1
SCHEMBL13153845 0.88 ACHE (0.50) ACHEEPHX2
SCHEMBL8960640 0.86 ACHE (0.57) ACHEEPHX2EPHX1
SCHEMBL8960685 0.86 ACHE (0.57) ACHEEPHX2EPHX1
SCHEMBL8960621 0.86 ACHE (0.57) ACHEEPHX2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024038465-A1 AN ANTIMICROBIAL COATING COMPOSITION HINDUSTAN PETROLEUM CORPORATION LIMITED (IN) 2024-02-22 WO claimed
EP-1451163-A4 3-AMIDO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF DONG WHA PHARM IND CO LTD (KR) 2005-01-26 EP claimed
EP-1451163-A1 3-AMIDO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) 2004-09-01 EP claimed
WO-2003040113-A1 3-AMIDO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF DONG WHA PHARM. IND. CO., LTD. (KR) 2003-05-15 WO claimed
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed
WO-2024043313-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, MICROENCAPSULATED PIGMENT USING SAID REVERSIBLE THERMOCHROMIC COMPOSITION, WRITING TOOL, AND TOY 三菱ケミカル株式会社 2024-02-29 WO disclosed
WO-2024038465-A1 AN ANTIMICROBIAL COATING COMPOSITION HINDUSTAN PETROLEUM CORPORATION LIMITED (IN) 2024-02-22 WO disclosed
CN-110526903-A Bisindole maleimide derivative and its preparation method and application OCEAN UNIV CHINA 2019-12-03 CN disclosed
CN-110218206-A Bisindole maleimide derivative and its preparation method and application 中国海洋大学 2019-09-10 CN disclosed
CN-106083830-B Bisindolylmaleimide derivative and preparation method and application thereof 中国海洋大学 2019-07-12 CN disclosed
CN-106146475-B Bisindolylmaleimide derivative and preparation method and application thereof 中国海洋大学 2019-05-17 CN disclosed
WO-2018138739-A1 NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2018-08-02 WO disclosed
EP-0086660-B1 RENALLY ACTIVE TETRAPEPTIDES SMITHKLINE BECKMAN CORPORATION (US) 1985-07-24 EP disclosed
US-4483988-A Substituted derivatives of 4-t-alkoxycarbonyl-piperazin-2-ones RICHARDSON MERRELL INC. (US) 1984-11-20 US disclosed
US-4435571-A 5-(Substituted benzyl)-6-oxo-2-piperazine carboxylic acids and esters RICHARDSON MERRELL INC. (US) 1984-03-06 US disclosed
EP-0086660-A2 Renally active tetrapeptides SMITHKLINE BECKMAN CORPORATION (US) 1983-08-24 EP disclosed
US-4370312-A HAPTENS, TRACERS, ANTIBODIES AND STARTING MATERIALS FOR INTERFERONS Dr. Karl Thomae Gesellshaft mit beschrankter Haftung (DE) 1983-01-25 US disclosed
US-4341698-A Enkaphalin derivatives RICHARDSON-MERRELL INC. (US) 1982-07-27 US disclosed
US-4279998-A DIAZO LINKAGE COUPLING THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 1981-07-21 US disclosed
US-3971737-A [2-Methyl-Ala6 ]LRH AMERICAN HOME PRODUCTS CORPORATION (US) 1976-07-27 US disclosed