Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576882 | 1.00 | ACHE (0.65) | ACHEEPHX1EPHX2NPC1RAB9A | |
| SCHEMBL8913848 | 1.00 | ACHE (0.65) | ACHEEPHX1EPHX2NPC1RAB9A | |
| SCHEMBL8849277 | 0.98 | ACHE (0.61) | ACHEEPHX1EPHX2NPC1RAB9A | |
| SCHEMBL8960685 | 0.93 | ACHE (0.57) | ACHEEPHX1EPHX2NPC1RAB9A | |
| SCHEMBL8960640 | 0.93 | ACHE (0.57) | ACHEEPHX1EPHX2NPC1RAB9A | |
| SCHEMBL8960621 | 0.93 | ACHE (0.57) | ACHEEPHX1EPHX2NPC1RAB9A | |
| SCHEMBL461365 | 0.92 | ACHE (0.58) | ACHEEPHX1EPHX2 | |
| Hydrochloric Acid SCHEMBL2185194 | 0.91 | ACHE (0.56) | ACHEEPHX1EPHX2 | |
| SCHEMBL4751426 | 0.86 | ACHE (0.51) | ACHEEPHX1EPHX2 | |
| SCHEMBL13153845 | 0.84 | ACHE (0.50) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5230890-A | URETHANE DERIVATIVES FROM AMINO ACIDS, A PROCESS FOR THEIR PREPARATION AND COSMETIC OR PHARMACEUTICAL COMPOSITIONS FOR USE IN THE TREATMENT OF DRY SKIN | L'OREAL (FR) | 1993-07-27 | — | — | US | disclosed |
| EP-0408448-B1 | URETHANE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HUMECTANTS IN COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DRY SKIN | L'OREAL (FR) | 1993-05-05 | — | — | EP | disclosed |
| EP-0408448-A1 | Urethane derivatives, their preparation and their use as humectants in cosmetic and pharmaceutical compositions for the treatment of dry skin | L'OREAL (FR) | 1991-01-16 | — | — | EP | disclosed |