Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 7/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195614 | 0.82 | LMNA (0.46) | LMNAMAPK1RAB9AGPR119SLC6A15 | |
| SCHEMBL3992214 | 0.81 | LMNA (0.45) | LMNAMAPK1RAB9AGPR119SLC6A15 | |
| SCHEMBL3997516 | 0.81 | LMNA (0.45) | LMNAMAPK1RAB9AGPR119SLC6A15 | |
| SCHEMBL2985134 | 0.78 | LMNA (0.46) | LMNAMAPK1RAB9AGPR119SLC6A15 | |
| SCHEMBL9342278 | 0.78 | MAPK1 (0.46) | LMNAMAPK1RAB9ASLC6A15TSHR | |
| SCHEMBL8665411 | 0.78 | TSHR (0.59) | LMNAMAPK1RAB9AGPR119TSHR | |
| SCHEMBL1780077 | 0.78 | LMNA (0.43) | LMNAMAPK1RAB9AGPR119SLC6A15 | |
| SCHEMBL597800 | 0.76 | LMNA (0.45) | LMNAMAPK1RAB9AGPR119SLC6A15 | |
| SCHEMBL12551267 | 0.76 | RAB9A (0.42) | LMNAMAPK1RAB9AGPR119SLC6A15 | |
| Hydrochloric Acid SCHEMBL20488405 | 0.76 | LMNA (0.42) | LMNAMAPK1RAB9AGPR119SLC6A15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373234-B1 | UROKINASE INHIBITORS | WILEX AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-6861435-B2 | Urokinase inhibitors | PENTAPHARM AG (CH) | 2005-03-01 | — | — | US | disclosed |