Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275238 | 0.86 | ALDH1A1 (0.42) | CYP1A2CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL12347952 | 0.82 | ALDH1A1 (0.40) | CYP1A2CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL23254247 | 0.81 | ALDH1A1 (0.42) | CYP1A2CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL21664800 | 0.78 | CYP1A2 (0.45) | CYP1A2CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL2980367 | 0.78 | CYP1A2 (0.42) | CYP1A2CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL21722426 | 0.78 | CHRNB2 (0.41) | CYP1A2CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL4817856 | 0.78 | TSHR (0.59) | CYP1A2LMNATSHRALDH1A1POLB | |
| SCHEMBL21205899 | 0.76 | CYP1A2 (0.38) | CYP1A2CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL18587334 | 0.76 | GAA (0.45) | CYP1A2CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL74877 | 0.76 | TSHR (0.57) | GAALMNATSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373234-B1 | UROKINASE INHIBITORS | WILEX AG (DE) | 2008-02-13 | — | — | EP | disclosed |