Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 5/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615881 | 0.94 | VDR (0.58) | VDRBCL2MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4613582 | 0.92 | VDR (0.57) | VDRBCL2MAPTMEN1KMT2A | |
| Iodide SCHEMBL6248897 | 0.92 | VDR (0.57) | VDRBCL2MAPTMEN1KMT2A | |
| Bromide SCHEMBL4614412 | 0.92 | VDR (0.57) | VDRBCL2MAPTMEN1KMT2A | |
| Sulfuric Acid SCHEMBL4616814 | 0.87 | VDR (0.52) | VDRBCL2MAPTMEN1KMT2A | |
| SCHEMBL5849880 | 0.85 | CYP1A1 (0.48) | VDRMAPTMEN1KMT2AKDM4E | |
| Sulfuric Acid SCHEMBL4617371 | 0.84 | VDR (0.50) | VDRBCL2MAPTMEN1KMT2A | |
| SCHEMBL4616667 | 0.81 | MAPT (0.58) | VDRBCL2MAPTMEN1KMT2A | |
| SCHEMBL4614019 | 0.81 | MAPT (0.58) | VDRBCL2MAPTMEN1KMT2A | |
| SCHEMBL12866325 | 0.76 | VDR (0.44) | VDRMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699427-B1 | AGENT AND METHOD FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AG (DE) | 2008-02-27 | — | — | EP | claimed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | claimed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | claimed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | KRT18, KIT, AOC1 | VDR 3539/4885BCL2 2663/4885MAPT 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.