SCHEMBL4614445

SCHEMBL4614445

CC(C)(C)[C@H](NC(=O)C(CC(=O)NO)CC1CCCC1)C(=O)N1CCC(NC(=O)c2ccc(Br)cc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 12/20 0.49
MMP3 P08254 8/20 0.49
BMP1 P13497 1/20 0.46
LTA4H P09960 1/20 0.43
PDF Q9HBH1 2/20 0.42
MMP1 P03956 9/20 0.41
FCER2 P06734 2/20 0.41
MMP13 P45452 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4880474 1.00 MMP2 (0.49) MMP2MMP3BMP1LTA4HPDF
SCHEMBL4888079 0.93 MMP2 (0.49) MMP2MMP3BMP1LTA4HPDF
SCHEMBL4887777 0.92 MMP2 (0.48) MMP2MMP3BMP1LTA4HPDF
SCHEMBL4879662 0.92 MMP2 (0.56) MMP2MMP3BMP1LTA4HMMP1
SCHEMBL4614374 0.92 MMP2 (0.56) MMP2MMP3BMP1LTA4HMMP1
SCHEMBL4887647 0.92 MMP2 (0.48) MMP2MMP3BMP1LTA4HPDF
SCHEMBL4878458 0.91 MMP3 (0.49) MMP2MMP3BMP1MMP1
SCHEMBL14066493 0.90 MMP2 (0.46) MMP2MMP3BMP1LTA4HMMP1
SCHEMBL4887577 0.88 MMP2 (0.51) MMP2MMP3BMP1MMP1MMP13
SCHEMBL14066489 0.87 MMP3 (0.51) MMP2MMP3BMP1PDFMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915342-A1 A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF Ildong Pharmaceutical Co., Ltd. (KR) 2008-04-30 EP disclosed
WO-2006115353-A1 A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF ILDONG PHARMACEUTICAL CO., LTD. (KR) 2006-11-02 WO disclosed