Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012824 | 0.80 | KMT2A (0.46) | LMNASMN1; SMN2L3MBTL1KDM4EHTT | |
| SCHEMBL1823997 | 0.74 | HTT (0.46) | LMNAHPGDCA12CA1CA2 | |
| SCHEMBL28162412 | 0.74 | SMN1; SMN2 (0.32) | PTGESALOX5PTGS1STAT3NFE2L2 | |
| SCHEMBL8440991 | 0.72 | TDP1 (0.35) | LMNACA1CA2HTTMEN1 | |
| SCHEMBL11147541 | 0.72 | GAA (0.46) | LMNASMN1; SMN2MAPK1L3MBTL1KDM4E | |
| SCHEMBL8435611 | 0.71 | ACP1 (0.36) | HPGDHSD17B10CA12CA1CA2 | |
| SCHEMBL8439787 | 0.71 | MEP1B (0.38) | HSD17B10MEP1BACLYSMN1; SMN2HTT | |
| SCHEMBL1009042 | 0.69 | TDP1 (0.42) | LMNAHPGDHSD17B10CA12CA1 | |
| SCHEMBL4614538 | 0.69 | SLC2A1 (0.37) | LMNAPTGESALOX5PTGS1STAT3 | |
| SCHEMBL4614220 | 0.69 | KDM4E (0.36) | LMNAPTGESALOX5PTGS1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148142-B1 | METHOD FOR QUANTITATING TRIGLYCERIDE IN LIPOPROTEIN | KYOWA MEDEX CO LTD (JP) | 2008-02-27 | — | — | EP | disclosed |
| US-20050042703-A1 | Method for quantitating triglycerides in lipoproteins | KYOWA MEDEX CO., LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-6811994-B1 | COMPRISES ELIMINATING FREE GLYCEROL FROM A SAMPLE THEN ALLOWING IT TO REACT WITH LIPOPROTEIN LIPASE WHICH GENERATES HYDROGEN PEROXIDE; USED TO DETECT ARTERIOSCLEROSIS | KYOWA MEDEX CO., LTD. (JP) | 2004-11-02 | — | — | US | disclosed |
| EP-1148142-A1 | METHOD FOR QUANTITATING TRIGLYCERIDE IN LIPOPROTEIN | KYOWA MEDEX CO., LTD. (JP) | 2001-10-24 | — | — | EP | disclosed |