Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440991 | 0.82 | TDP1 (0.35) | HTTESR1TTRMEN1KMT2A | |
| SCHEMBL8435611 | 0.81 | ACP1 (0.36) | HSD17B10ALOX15ALDH1A1CYP2C9ALOX12 | |
| SCHEMBL1823997 | 0.78 | HTT (0.46) | GAAHTTCYP1A2CYP3A4POLB | |
| SCHEMBL1012824 | 0.74 | KMT2A (0.46) | ALDH1A1GAAHTTCYP1A2CYP2C9 | |
| SCHEMBL1009042 | 0.73 | TDP1 (0.42) | HSD17B10ALOX15ALDH1A1GAAPKM | |
| SCHEMBL4614536 | 0.71 | LMNA (0.34) | MEP1BHSD17B10ALDH1A1HTTACLY | |
| SCHEMBL27617207 | 0.70 | GAA (0.46) | HSD17B10ALOX15ALDH1A1GAAHTT | |
| SCHEMBL9551532 | 0.69 | GAA (0.45) | HSD17B10ALOX15ALDH1A1GAAHTT | |
| SCHEMBL3381681 | 0.68 | — | — | |
| SCHEMBL28075781 | 0.67 | ALDH1A1 (0.67) | HSD17B10ALOX15ALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858695-A | SUBJECTING BILIRUBIN TO COEXIST WITH ASCORBATE OXIDASE AND A REACTION PROMOTER IN AQUEOUS MEDIUM TO THEREBY OXIDIZE THE BILIRUBIN, MEASURING THE CHANGE IN ABSORBANCE | KYOWA MEDEX CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0770688-A1 | Method of quantitative determination of bilirubin and a reagent therefor | KYOWA MEDEX CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |