Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 16/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4613886 | 0.86 | PTGS2 (0.76) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL14289269 | 0.86 | PTGS2 (0.75) | PTGS2PTGS1ALOX5ACHE | |
| SCHEMBL4611751 | 0.84 | PTGS2 (0.72) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL4632013 | 0.81 | PTGS2 (0.67) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL7141533 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL441830 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4613415 | 0.73 | PTGS2 (0.57) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7137506 | 0.72 | PTGS2 (0.56) | PTGS2PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL4613343 | 0.71 | PTGS2 (0.55) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7134569 | 0.71 | PTGS2 (0.58) | PTGS2PTGS1ALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773939-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2008-02-06 | — | — | EP | disclosed |
| US-5674891-A | ANALGESICS WITH SIDE EFFECT REDUCTION | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5656661-A | ANALGESICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0773939-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003396-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |