Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 18/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441830 | 0.89 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4614766 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7161473 | 0.80 | PTGS2 (0.67) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7139884 | 0.78 | PTGS2 (0.63) | PTGS2PTGS1ALOX5 | |
| SCHEMBL3582386 | 0.78 | PTGS2 (0.63) | PTGS2PTGS1ALOX5 | |
| SCHEMBL3589022 | 0.77 | PTGS2 (0.62) | PTGS2PTGS1ALOX5 | |
| SCHEMBL3584479 | 0.77 | PTGS2 (0.62) | PTGS2PTGS1ALOX5 | |
| SCHEMBL8759729 | 0.76 | PTGS2 (0.73) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4611907 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL3592610 | 0.75 | PTGS2 (0.60) | PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907646-B1 | DIHYDROBENZOPYRAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2003-05-21 | — | — | EP | disclosed |