⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29245223 | 0.81 | ALDH1A1 (0.33) | — | |
| SCHEMBL995685 | 0.77 | — | — | |
| SCHEMBL1766638 | 0.75 | — | — | |
| SCHEMBL1126985 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL575181 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL113676 | 0.73 | — | — | |
| SCHEMBL11602769 | 0.73 | — | — | |
| SCHEMBL5933133 | 0.73 | — | — | |
| SCHEMBL11530469 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL609521 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879867-A2 | INTERMEDIATES FOR PREPARING SOLIFENACIN | Teva Pharmaceutical Industries Ltd (IL) | 2008-01-23 | — | — | EP | claimed |
| WO-2007076116-A2 | INTERMEDIATES FOR PREPARING SOLIFENACIN | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-07-05 | — | — | WO | claimed |
| EP-1879867-A2 | INTERMEDIATES FOR PREPARING SOLIFENACIN | Teva Pharmaceutical Industries Ltd (IL) | 2008-01-23 | — | — | EP | disclosed |
| US-20070173528-A1 | Process for preparing solifenacin | TEVA PHARMACEUTICALS USA, INC. | 2007-07-26 | — | — | US | disclosed |
| WO-2007076116-A2 | INTERMEDIATES FOR PREPARING SOLIFENACIN | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-07-05 | — | — | WO | disclosed |
| US-4111933-A | PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |