SCHEMBL575181

SCHEMBL575181

O=C(OCCCl)OCCCl

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.32
SOAT1 P35610 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575094 0.91
SCHEMBL11530469 0.90 ALDH1A1 (0.35) ALDH1A1TP53TSHR
SCHEMBL15180219 0.89 TSHR (0.41) ALDH1A1TSHRKMT2A
SCHEMBL9303937 0.88 SOAT1 (0.46) ALDH1A1TP53SOAT1
SCHEMBL575192 0.87
SCHEMBL9512898 0.87
SCHEMBL10836973 0.87 ALDH1A1 (0.43) ALDH1A1TSHRSOAT1
SCHEMBL9215552 0.84 TSHR (0.35) ALDH1A1TSHR
SCHEMBL575123 0.83
SCHEMBL4293436 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 518 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119447514-A Biphase electrolyte and electrochemical device 清华大学深圳国际研究生院 2025-02-14 CN claimed
WO-2024191025-A1 COSMETIC COMPOSITION COMPRISING CAPSULES OR BEADS 한국콜마주식회사 2024-09-19 WO claimed
CN-116144055-A Biaxially oriented crosslinked polyethylene film and preparation method thereof 国家能源投资集团有限责任公司 2023-05-23 CN claimed
CN-108659527-B High-strength glass fiber composite material and preparation method thereof 元源新材料有限公司 2021-01-05 CN claimed
CN-108467579-B Organic glass fiber composite material and preparation method thereof 贵州安顺开发区埃维森航空科技开发有限公司 2020-05-22 CN claimed
US-9907796-B2 Methods of treating tumoral diseases, or bacterial or viral infections INHIBIKASE THERAPEUTICS, INC. (US) 2018-03-06 US claimed
US-20170000789-A1 Methods of Treating Tumoral Diseases, or Bacterial or Viral Infections SPHAERA PHARMA PTE. LTD. (SG) 2017-01-05 US claimed
WO-2016151508-A1 METHOD AND APPARATUS FOR THE PRODUCTION OF DIARYL CARBONATE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-29 WO claimed
US-9359376-B2 Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds SPHAERA PHARMA PTE. LTD (SG) 2016-06-07 US claimed
EP-2903979-A1 NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES Inhibikase Therapeutics, Inc. (US) 2015-08-12 EP claimed
US-20140121367-A1 SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS PIVOT HOLDING LLC 2014-05-01 US claimed
US-20140100225-A1 NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES INHIBIKASE THERAPEUTICS, INC. (US) 2014-04-10 US claimed
WO-2014055938-A1 NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES INHIBIKASE THERAPEUTICS, INC. (US) 2014-04-10 WO claimed
EP-2693876-A1 SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS Sphaera Pharma Pte. Ltd (SG) 2014-02-12 EP claimed
WO-2012137225-A1 SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS SPHAERA PHARMA PVT. LTD (IN) 2012-10-11 WO claimed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US claimed
US-4028299-A CATALYST-FREE, LIQUID CARBONATE AS MODIFIER THE DOW CHEMICAL COMPANY (US) 1977-06-07 US claimed
US-3983066-A Solid, rapid setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US claimed
US-12629371-B2 Compositions and methods for inhibiting kinases INHIBIKASE THERAPEUTICS, INC. (US) 2026-05-19 US disclosed
US-3956221-A Rapid setting non-elastomeric polyurethane compositions containing a non-hydroxyl containing ester-modified polyoxylkylene compound THE DOW CHEMICAL COMPANY (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140121367-A1 SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS TPMT, BHMT2, PFAS ALDH1A1 524/4885TP53 3939/4885TSHR 3151/4885
US-20170000789-A1 Methods of Treating Tumoral Diseases, or Bacterial or Viral Infections POLI, RNASE1, VHL ALDH1A1 1777/4885TP53 73/4885TSHR 4292/4885
US-12629371-B2 Compositions and methods for inhibiting kinases PTK2, HCK, PTK2B ALDH1A1 1607/4885TP53 3975/4885TSHR 2320/4885
US-20140100225-A1 NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES POLI, MCL1, HRAS ALDH1A1 2478/4885TP53 5/4885TSHR 4553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.