Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CAD | P27708 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23629663 | 0.85 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCADALOX15 | |
| SCHEMBL23155981 | 0.85 | FOLH1 (0.45) | L3MBTL1KMT2AALOX15BMP1BLM | |
| SCHEMBL7608495 | 0.84 | L3MBTL1 (0.56) | L3MBTL1KMT2APOLBCADALOX15 | |
| SCHEMBL28539939 | 0.83 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL17343482 | 0.83 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCADALOX15 | |
| SCHEMBL22316082 | 0.83 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL13099456 | 0.83 | L3MBTL1 (0.69) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL13108405 | 0.83 | L3MBTL1 (0.69) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL468758 | 0.82 | L3MBTL1 (0.54) | L3MBTL1KMT2APOLBCADALOX15 | |
| SCHEMBL468757 | 0.82 | L3MBTL1 (0.54) | L3MBTL1KMT2APOLBCADALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595960-A1 | SALT AND SOLVATES OF A TETRAHYDROISOQUINOLINE DERIVATIVE | Spinifex Pharmaceuticals Pty Ltd (AU) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010843-A1 | SALT AND SOLVATES OF A TETRAHYDROISOQUINOLINE DERIVATIVE | SPINIFEX PHARMACEUTICALS PTY LTD (AU) | 2012-01-26 | — | — | WO | disclosed |