Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CAD | P27708 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468758 | 0.88 | L3MBTL1 (0.54) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL468757 | 0.88 | L3MBTL1 (0.54) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL4180273 | 0.86 | L3MBTL1 (0.61) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL4180270 | 0.86 | L3MBTL1 (0.61) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL11698768 | 0.85 | KMT2A (0.41) | L3MBTL1KMT2APOLBFOLH1ALOX15 | |
| SCHEMBL23629663 | 0.84 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL7599579 | 0.84 | L3MBTL1 (0.77) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL461495 | 0.84 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL13195868 | 0.82 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCADNOD1 | |
| SCHEMBL28879483 | 0.82 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCADNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266900-A1 | Carbamates of rapamycin | Wyeth (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5411967-A | Antiinflammatory, immunosuppressant, antitumor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0593227-A1 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5302584-A | Immunosuppressants | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |