Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616199 | 0.88 | MAPK14 (0.47) | EPHX2PPARAPPARDPPARGMAPK14 | |
| SCHEMBL5412175 | 0.76 | PPARA (0.61) | HTR2CPPARAPPARDPPARG | |
| SCHEMBL3575043 | 0.72 | EPHX2 (0.57) | EPHX2NR1H4HTR2CPDE2APPARA | |
| SCHEMBL22972197 | 0.71 | KDR (0.46) | PPARAPPARDPPARGMAPK14 | |
| SCHEMBL3966634 | 0.70 | EPHX2 (0.63) | EPHX2NR1H4HTR2CPDE2APPARA | |
| SCHEMBL6635990 | 0.69 | EPHX2 (0.61) | EPHX2NR1H4HTR2CPDE2APPARA | |
| SCHEMBL3577590 | 0.69 | EPHX2 (0.73) | EPHX2NR1H4HTR2CPPARAPPARG | |
| SCHEMBL15953377 | 0.68 | LIPG (0.75) | EPHX2NR1H4HTR2CPDE2APPARA | |
| SCHEMBL934006 | 0.68 | EPHX2 (0.60) | EPHX2NR1H4HTR2CPDE2APPARA | |
| SCHEMBL921976 | 0.68 | MAPK8 (0.52) | EPHX2NR1H4HTR2CPDE2AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697304-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-02-20 | — | — | EP | disclosed |