Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933617 | 0.88 | EPHX2 (0.58) | EPHX2NR1H4PPARAPPARGCA12 | |
| SCHEMBL934356 | 0.85 | HPGD (0.65) | EPHX2NR1H4PPARAPPARGCA12 | |
| SCHEMBL31036991 | 0.85 | ADRB2 (0.47) | EPHX2NR1H4PPARAPPARGCA12 | |
| SCHEMBL31248368 | 0.84 | EPHX2 (0.57) | EPHX2NR1H4PPARAPPARGCA12 | |
| SCHEMBL19212325 | 0.84 | EPHX2 (0.57) | EPHX2NR1H4PPARAPPARGCA12 | |
| SCHEMBL23564738 | 0.84 | EPHX2 (0.57) | EPHX2NR1H4PPARAPPARGCA12 | |
| SCHEMBL13968725 | 0.84 | EPHX2 (0.54) | EPHX2NR1H4PPARAPPARGCA12 | |
| SCHEMBL3966634 | 0.84 | EPHX2 (0.63) | EPHX2NR1H4PPARAPPARGCA12 | |
| SCHEMBL8244679 | 0.84 | HPGD (0.64) | EPHX2NR1H4PPARAPPARGCA12 | |
| SCHEMBL27859550 | 0.83 | EPHX2 (0.62) | EPHX2NR1H4PPARAPPARGCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118561801-A | Benzo [ d ] [1,3] dioxoles compound, preparation method and application thereof | 上海医药集团股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2011037833-A2 | NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-03-31 | — | — | WO | disclosed |
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |