SCHEMBL4615339

SCHEMBL4615339

CC(=O)N1C(C)(C)CC2(CC1(C)C)OC1(CCCCCCCCCCC1)NC2=O

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8880025 1.00 CYP3A4 (0.31) CYP3A4MEN1KMT2ASMN1; SMN2
SCHEMBL11190759 0.90 ESR1 (0.32) CYP3A4MEN1KMT2ASMN1; SMN2
SCHEMBL6306972 0.84
SCHEMBL4339514 0.82
SCHEMBL8879540 0.81 ESR1 (0.32)
SCHEMBL10579834 0.79
SCHEMBL10151276 0.79
SCHEMBL10151277 0.79
SCHEMBL11384939 0.78
SCHEMBL11192057 0.78 ESR1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080203593-A1 Polyvinyl Acetal-Containing Granulate, Method for the Production and the Utilization Thereof KURARAY EUROPE GMBH (DE) 2008-08-28 US disclosed
EP-1658323-B1 POLYVINYL ACETAL-CONTAINING GRANULATE, METHOD FOR THE PRODUCTION AND THE UTILIZATION THEREOF KURARAY EUROPE GMBH (DE) 2008-02-20 EP disclosed
US-7297734-B2 Process for preparing synergistic stabilizer mixtures CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-11-20 US disclosed
EP-1474471-B8 PROCESS FOR PREPARING A SYNERGISTIC STABILIZER MIXTURE CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-10-04 EP disclosed
US-7105590-B2 Phenolfree stabilization of polyolefins CLARIANT FINANCE (BVI) LIMITED (VG) 2006-09-12 US disclosed
EP-0718357-B1 Flame-resistant moulding composition having improved light stability CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-07-19 EP disclosed
EP-1658323-A1 POLYVINYL ACETAL-CONTAINING GRANULATE, METHOD FOR THE PRODUCTION AND THE UTILIZATION THEREOF Kuraray Specialities Europe GmbH (DE) 2006-05-24 EP disclosed
EP-1474471-B1 SELECTIVE OXIDATION OF SODIUM SULFIDE IN KRAFT COOKING LIQUORS CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-05-03 EP disclosed
US-20050250889-A1 Synergistc stabilizer composition for color stable pigmented thermophastic polymers in prolonged contact with water CLARIANT FINANCE (BVI) LIMITED (VG) 2005-11-10 US disclosed
US-20050228086-A1 Selective oxidation of sodium sulfide in kraft cooking liquors CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2005-10-13 US disclosed
EP-0524640-A1 Diarylphosphinous acid arylesters, process for their preparation and their use to stabilize polymers, in particular polyolefin moulding compositions HOECHST AKTIENGESELLSCHAFT (DE) 1993-01-27 EP disclosed
EP-0517128-A2 Use of a carboxylic acid anhydride to manufacture a polyolefin moulding composition HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-09 EP disclosed
EP-0489050-A1 ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-10 EP disclosed
EP-0485891-A2 Process for the reduction of discoloration of a polymeric moulding composition at processing temperature HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-20 EP disclosed
WO-1991002738-A1 ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-07 WO disclosed
EP-0402889-A2 Polymeric polyalkyl-1-oxadiazaspirodecanes HOECHST AKTIENGESELLSCHAFT (DE) 1990-12-19 EP disclosed
WO-1990014349-A2 ARYLESTERS OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS, IN PARTICULAR POLYOLEFIN MOULDING MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-29 WO disclosed
US-4689416-A PHASE TRANSFER CATALYST HOECHST AKTIENGELLSCHAFT (DE) 1987-08-25 US disclosed
US-4419512-A PHOTOSTABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-12-06 US disclosed
EP-0079850-A1 N-substituted polyalkylpiperidine-4-spirooxazolones CIBA-GEIGY AG (CH) 1983-05-25 EP disclosed