SCHEMBL8879540

SCHEMBL8879540

CC(=O)N1C(C)(C)CC2(CC1(C)C)OC(C)(C)NC2=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8880025 0.81 CYP3A4 (0.31)
SCHEMBL4615339 0.81 CYP3A4 (0.31)
SCHEMBL11192057 0.77 ESR1 (0.32) ESR1
SCHEMBL11190759 0.76 ESR1 (0.32) ESR1
SCHEMBL893546 0.75
SCHEMBL16313211 0.73
SCHEMBL5647311 0.72 SMN1; SMN2 (0.32)
SCHEMBL11374165 0.71 POLB (0.31)
SCHEMBL11188359 0.66 CYP3A4 (0.31)
SCHEMBL12802539 0.66 ESR1 (0.33) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5644060-A NO PHASE TRANSFER CATALYST HOECHST ATKIENGESELLSCHAFT (DE) 1997-07-01 US disclosed
US-4689416-A PHASE TRANSFER CATALYST HOECHST AKTIENGELLSCHAFT (DE) 1987-08-25 US disclosed
US-4419512-A PHOTOSTABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-12-06 US disclosed
EP-0079850-A1 N-substituted polyalkylpiperidine-4-spirooxazolones CIBA-GEIGY AG (CH) 1983-05-25 EP disclosed