SCHEMBL8880025

SCHEMBL8880025

CC(=O)N1C(C)(C)CC2(CC1(C)C)OC1(CCCCC1)NC2=O

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4615339 1.00 CYP3A4 (0.31) CYP3A4MEN1KMT2ASMN1; SMN2
SCHEMBL11190759 0.90 ESR1 (0.32) CYP3A4MEN1KMT2ASMN1; SMN2
SCHEMBL6306972 0.84
SCHEMBL4339514 0.82
SCHEMBL8879540 0.81 ESR1 (0.32)
SCHEMBL10579834 0.79
SCHEMBL10151276 0.79
SCHEMBL10151277 0.79
SCHEMBL11384939 0.78
SCHEMBL11192057 0.78 ESR1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5644060-A NO PHASE TRANSFER CATALYST HOECHST ATKIENGESELLSCHAFT (DE) 1997-07-01 US disclosed
US-4689416-A PHASE TRANSFER CATALYST HOECHST AKTIENGELLSCHAFT (DE) 1987-08-25 US disclosed