Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6117220 | 0.97 | TSHR (0.47) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6117341 | 0.84 | TSHR (0.48) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1483412 | 0.84 | TSHR (0.52) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6117844 | 0.83 | TSHR (0.44) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL2140805 | 0.82 | TSHR (0.54) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Water SCHEMBL31228205 | 0.80 | TSHR (0.52) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| Bromide SCHEMBL29482780 | 0.79 | ZDHHC20 (0.44) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| Bromide SCHEMBL29482779 | 0.79 | ZDHHC20 (0.44) | TSHRZDHHC20ZDHHC2ALDH1A1MAPK1 | |
| Hydrogen Sulfide SCHEMBL28195736 | 0.77 | TSHR (0.58) | TSHRACACBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL8401460 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1543983-B1 | Ink-jet recording medium and process for producing the same | FUJIFILM CORP (JP) | 2008-02-20 | — | — | EP | disclosed |
| US-20050158489-A1 | Ink-jet recording medium and process for producing the same | FUJI PHOTO FILM CO., LTD. | 2005-07-21 | — | — | US | disclosed |
| EP-1543983-A1 | Ink-jet recording medium and process for producing the same | Fuji Photo Film Co., Ltd. (JP) | 2005-06-22 | — | — | EP | disclosed |