Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | TACR2 | P21452 | 3/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | GJB2 | P29033 | 1/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.43 |
| ▸ | CDC25B | P30305 | 6/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410621 | 1.00 | HTR1A (0.48) | HTR1ANT5ETACR2PDE2AGJB2 | |
| SCHEMBL18636425 | 0.96 | PDE2A (0.48) | HTR1ANT5ETACR2PDE2AGJB2 | |
| SCHEMBL17039975 | 0.96 | PDE2A (0.48) | HTR1ANT5ETACR2PDE2AGJB2 | |
| SCHEMBL16756817 | 0.96 | PDE2A (0.48) | HTR1ANT5ETACR2PDE2AGJB2 | |
| SCHEMBL16756820 | 0.96 | PDE2A (0.48) | HTR1ANT5ETACR2PDE2AGJB2 | |
| SCHEMBL24371602 | 0.96 | PDE2A (0.48) | HTR1ANT5ETACR2PDE2AGJB2 | |
| SCHEMBL29711813 | 0.96 | PDE2A (0.48) | HTR1ANT5ETACR2PDE2AGJB2 | |
| SCHEMBL20870545 | 0.89 | HTR1A (0.43) | HTR1ANT5ETACR2PDE2AGJB2 | |
| SCHEMBL14278490 | 0.89 | HTR1A (0.43) | HTR1ANT5ETACR2PDE2AGJB2 | |
| SCHEMBL19736552 | 0.89 | HTR1A (0.43) | HTR1ANT5ETACR2PDE2AGJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583303-B | Tripterine conjugates and uses thereof | 瑞阳公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-117858882-A | Prodrugs having 1- (disulfanyl) alkoxy-carbonyl units | 药物有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-116583303-A | Tripterine conjugates and uses thereof | 瑞阳公司 | 2023-08-11 | — | — | CN | disclosed |
| EP-4200022-A1 | TRIPTOLIDE CONJUGATES AND USES THEREOF | Reyoung Corporation (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022271018-A1 | PRODRUGS WITH 1-(DISULFANYL)ALKYLOXY-CARBONYL UNITS | PHARMACYTICS B.V. (NL) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022040487-A1 | TRIPTOLIDE CONJUGATES AND USES THEREOF | REYOUNG CORPORATION (US) | 2022-02-24 | — | — | WO | disclosed |
| WO-2008132541-A2 | CONJUGATES OF 2-FLUORO-2-DEOXY-GLUCOSE AND THEIR USES AS ANTI CANCER AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-11-06 | — | — | WO | disclosed |
| EP-1881000-A1 | Conjugates of 2-fluoro-2-deoxy-glucose and their uses as anti cancer agents | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-01-23 | — | — | EP | disclosed |
| EP-0837867-B1 | MODIFIED ALPHA-D-Glcp-(1-2)-ALPHA-D-Glcp-(1-3)-ALPHA-D-Glcp-ANALOGUES | ALBERTA RES COUNCIL (CA) | 2001-08-16 | — | — | EP | disclosed |
| US-5929037-A | GLUCOSIDASE I INHIBITORS | ALBERTA RESEARCH COUNCIL (CA) | 1999-07-27 | — | — | US | disclosed |
| EP-0837867-A1 | MODIFIED $g(a)-D-Glcp-(1-2)-$g(a)-D-Glcp-(1-3)-$g(a)-D-Glcp-ANALOGUES | ALBERTA RESEARCH COUNCIL (CA) | 1998-04-29 | — | — | EP | disclosed |
| WO-1996040700-A1 | MODIFIED α-D-Glcp-(1-2)-α-D-Glcp-(1-3)-α-D-Glcp-ANALOGUES | ALBERTA RESEARCH COUNCIL (CA) | 1996-12-19 | — | — | WO | disclosed |