Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | GJB2 | P29033 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 3/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | CDC25B | P30305 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14278490 | 1.00 | HTR1A (0.43) | HTR1ANT5EPDE2AGJB2BCHE | |
| SCHEMBL20870545 | 1.00 | HTR1A (0.43) | HTR1ANT5EPDE2AGJB2BCHE | |
| SCHEMBL29410621 | 0.89 | HTR1A (0.48) | HTR1ANT5EPDE2AGJB2BCHE | |
| SCHEMBL4615596 | 0.89 | HTR1A (0.48) | HTR1ANT5EPDE2AGJB2BCHE | |
| SCHEMBL13204990 | 0.89 | HTR1A (0.52) | HTR1ANT5EGJB2BCHEACHE | |
| SCHEMBL20223437 | 0.89 | HTR1A (0.52) | HTR1ANT5EGJB2BCHEACHE | |
| SCHEMBL17040197 | 0.89 | HTR1A (0.52) | HTR1ANT5EGJB2BCHEACHE | |
| SCHEMBL1561736 | 0.89 | HTR1A (0.52) | HTR1ANT5EGJB2BCHEACHE | |
| SCHEMBL1561732 | 0.89 | HTR1A (0.52) | HTR1ANT5EGJB2BCHEACHE | |
| SCHEMBL13591465 | 0.89 | HTR1A (0.52) | HTR1ANT5EGJB2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180170957-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS | ACADEMIA SINICA (TW) | 2018-06-21 | — | — | US | disclosed |
| US-20170360924-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | ACADEMIA SINICA (TW) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360924-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS | UGCG, GALK1, B3GAT3 | HTR1A 4652/4885NT5E 1606/4885PDE2A 2251/4885 |
| US-20180170957-A1 | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS | CD69, PBK, CCL11 | HTR1A 4794/4885NT5E 1331/4885PDE2A 2564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.