Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5292407 | 0.72 | ALDH1A1 (0.39) | HTTCYP1A2CYP2D6ALDH1A1GABRA5 | |
| SCHEMBL4621924 | 0.70 | ALDH1A1 (0.59) | CYP1A2ALDH1A1GABRA5KDM4EMAPT | |
| SCHEMBL6740402 | 0.70 | ALDH1A1 (0.53) | HTTCYP1A2CYP2D6ALDH1A1GABRA5 | |
| SCHEMBL30935713 | 0.70 | HTT (0.48) | HTTCYP1A2CYP2D6ALDH1A1GABRA5 | |
| SCHEMBL4616230 | 0.70 | GPR3 (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL4615823 | 0.70 | ALDH1A1 (0.53) | HTTCYP1A2CYP2D6ALDH1A1KDM4E | |
| SCHEMBL4615827 | 0.70 | ALDH1A1 (0.53) | HTTCYP1A2CYP2D6ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5899799 | 0.69 | KMT2A (0.55) | CYP1A2ALDH1A1KDM4EMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5899798 | 0.69 | KMT2A (0.55) | CYP1A2ALDH1A1KDM4EMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11514668 | 0.68 | GPR3 (0.42) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601335-B1 | MEANS AND METHOD FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES | WELLA AG (DE) | 2008-03-19 | — | — | EP | claimed |
| EP-1601335-B1 | MEANS AND METHOD FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES | WELLA AG (DE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1699427-B1 | AGENT AND METHOD FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AG (DE) | 2008-02-27 | — | — | EP | disclosed |