Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6104417 | 0.87 | SFRP1 (0.58) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL29451402 | 0.84 | MEN1 (0.55) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL6102235 | 0.84 | MEN1 (0.55) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL29451596 | 0.83 | PRMT5 (0.58) | MEN1KMT2ARAB9ALMNATDP1 | |
| SCHEMBL4616179 | 0.83 | RAB9A (0.53) | MEN1KMT2ARAB9ALMNATDP1 | |
| SCHEMBL4618303 | 0.83 | RAB9A (0.53) | MEN1KMT2ARAB9ALMNATDP1 | |
| SCHEMBL29451524 | 0.83 | MEN1 (0.60) | MEN1KMT2ARAB9ALMNATDP1 | |
| SCHEMBL29451605 | 0.81 | KDM4E (0.75) | MEN1KMT2ARAB9AKDM4EMAPT | |
| SCHEMBL4618304 | 0.81 | SFRP1 (0.71) | MEN1KMT2ARAB9ATDP1KDM4E | |
| SCHEMBL4618980 | 0.81 | RAB9A (0.51) | MEN1KMT2ARAB9ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |