Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.59 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 9/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3335173 | 0.90 | LMNA (0.48) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL23266068 | 0.89 | MEN1 (0.67) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL16559902 | 0.86 | KDM4E (0.50) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL3096757 | 0.86 | KDM4E (0.50) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL12703442 | 0.85 | APP (0.57) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL6658231 | 0.85 | HRH3 (0.59) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL6133622 | 0.84 | HRH3 (0.53) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL3611926 | 0.83 | KDM4E (0.61) | MAPK1APPKDM4ERECQLL3MBTL1 | |
| SCHEMBL12703538 | 0.83 | KDM4E (0.61) | MAPK1APPKDM4ERECQLL3MBTL1 | |
| SCHEMBL23291231 | 0.83 | TAAR1 (0.56) | LMNAMEN1USP2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221702-A1 | COMPOUNDS | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221702-A1 | COMPOUNDS | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| EP-1879562-A2 | PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY | Imperial Innovations Limited (GB) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006097744-A2 | PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY | IMPERIAL INNOVATIONS LIMITED (GB) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221702-A1 | COMPOUNDS | NCEH1, NME2, HRH3 | LMNA 4129/4885MEN1 550/4885USP2 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.