Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.38 |
| ▸ | SCD | O00767 | 4/20 | 0.36 |
| ▸ | DCK | P27707 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 6/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425555 | 0.73 | FAAH (0.43) | — | |
| SCHEMBL461349 | 0.71 | TSHR (0.38) | GPR6 | |
| SCHEMBL17772980 | 0.63 | PIK3CB (0.48) | CHRM4SCD | |
| SCHEMBL5986520 | 0.62 | ACACB (0.53) | CHRM4LIPG | |
| SCHEMBL28187923 | 0.62 | CHRM4 (0.46) | CHRM4DCKSCN9A | |
| SCHEMBL3376459 | 0.60 | TP53 (0.48) | SCD | |
| SCHEMBL7603271 | 0.60 | ACACB (0.51) | LIPG | |
| SCHEMBL23564134 | 0.59 | MAPT (0.47) | CHRM4 | |
| SCHEMBL19023226 | 0.58 | CHRM4 (0.72) | CHRM4SCDLIPG | |
| SCHEMBL19022841 | 0.58 | CHRM4 (0.75) | CHRM4GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | CHRM4 2063/4885SCD 28/4885DCK 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.