Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.50 |
| ▸ | MMP3 | P08254 | 7/20 | 0.50 |
| ▸ | MMP1 | P03956 | 4/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4880753 | 1.00 | MMP2 (0.50) | MMP2MMP3MMP1MMP9MMP8 | |
| SCHEMBL4887742 | 0.92 | MMP2 (0.49) | MMP2MMP3MMP1MMP9MMP8 | |
| SCHEMBL4887577 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP1MMP9MMP8 | |
| SCHEMBL4877176 | 0.91 | MMP2 (0.53) | MMP2MMP3MMP1MMP9MMP8 | |
| SCHEMBL4618893 | 0.89 | MMP2 (0.48) | MMP2MMP3MMP1MMP9MMP8 | |
| SCHEMBL4884939 | 0.89 | MMP3 (0.52) | MMP2MMP3MMP1MMP9MMP7 | |
| SCHEMBL4887777 | 0.88 | MMP2 (0.48) | MMP2MMP3MMP1KMT2ATSHR | |
| SCHEMBL4886049 | 0.85 | KMT2A (0.43) | KMT2ATSHRUSP2POLBMEN1 | |
| SCHEMBL4886058 | 0.85 | KMT2A (0.43) | KMT2ATSHRUSP2POLBMEN1 | |
| SCHEMBL4884035 | 0.83 | MMP2 (0.56) | MMP2MMP3MMP1MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915342-A1 | A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2008-04-30 | — | — | EP | disclosed |
| WO-2006115353-A1 | A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2006-11-02 | — | — | WO | disclosed |