Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 17/20 | 0.49 |
| ▸ | CA1 | P00915 | 17/20 | 0.49 |
| ▸ | CA2 | P00918 | 17/20 | 0.49 |
| ▸ | CA9 | Q16790 | 15/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 12/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617466 | 1.00 | CA12 (0.49) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4617981 | 0.86 | CA12 (0.52) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4617983 | 0.86 | CA12 (0.52) | CA12CA1CA2CA9CA14 | |
| SCHEMBL7051012 | 0.81 | CA12 (0.65) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4617424 | 0.79 | LMNA (0.52) | CA12CA1CA2CA9TSHR | |
| SCHEMBL4617428 | 0.79 | LMNA (0.52) | CA12CA1CA2CA9TSHR | |
| SCHEMBL22556155 | 0.76 | NT5E (0.55) | CA12CA1CA2CA9CA14 | |
| SCHEMBL7056168 | 0.76 | TSHR (0.62) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28622970 | 0.76 | NT5E (0.52) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4812797 | 0.75 | CA12 (0.41) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881000-A1 | Conjugates of 2-fluoro-2-deoxy-glucose and their uses as anti cancer agents | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-01-23 | — | — | EP | disclosed |