Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617475 | 1.00 | LMNA (0.55) | LMNAALDH1A1POLBTSHRCA12 | |
| SCHEMBL6436212 | 0.90 | LMNA (0.58) | LMNAALDH1A1POLBTSHRCA12 | |
| SCHEMBL16023529 | 0.90 | LMNA (0.58) | LMNAALDH1A1POLBTSHRCA12 | |
| SCHEMBL16023528 | 0.90 | LMNA (0.58) | LMNAALDH1A1POLBTSHRCA12 | |
| SCHEMBL10119659 | 0.90 | LMNA (0.58) | LMNAALDH1A1POLBTSHRCA12 | |
| SCHEMBL6437585 | 0.90 | LMNA (0.58) | LMNAALDH1A1POLBTSHRCA12 | |
| SCHEMBL6898150 | 0.90 | LMNA (0.58) | LMNAALDH1A1POLBTSHRCA12 | |
| SCHEMBL6437587 | 0.90 | LMNA (0.58) | LMNAALDH1A1POLBTSHRCA12 | |
| SCHEMBL6436210 | 0.90 | LMNA (0.58) | LMNAALDH1A1POLBTSHRCA12 | |
| SCHEMBL11042081 | 0.85 | ALDH1A1 (0.54) | LMNAALDH1A1POLBCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881000-A1 | Conjugates of 2-fluoro-2-deoxy-glucose and their uses as anti cancer agents | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-01-23 | — | — | EP | disclosed |