Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | CDK4 | P11802 | 5/20 | 0.36 |
| ▸ | CCND1 | P24385 | 5/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945781 | 0.81 | CYP2A6 (0.55) | PLGPLAUHTR2CHTR2AMTNR1A | |
| SCHEMBL2950156 | 0.81 | PLG (0.38) | PLGPLAUHTR2CHTR2ACDK4 | |
| SCHEMBL8463092 | 0.81 | HTR2C (0.57) | HTR2CHTR2AMTNR1AMTNR1BHTR7 | |
| SCHEMBL27718498 | 0.80 | PLG (0.48) | PLGPLAU | |
| Hydrochloric Acid SCHEMBL2948588 | 0.79 | PLG (0.38) | PLGPLAUHTR2CHTR2ACDK4 | |
| SCHEMBL2941157 | 0.79 | PLG (0.45) | PLGPLAULMNAHTR7 | |
| SCHEMBL27452399 | 0.79 | MTNR1A (0.43) | PLGPLAUHTR2CHTR2ACDK4 | |
| SCHEMBL2950302 | 0.78 | P2RX7 (0.46) | PLGPLAUHTR2CHTR2A | |
| SCHEMBL2946887 | 0.78 | CDK4 (0.63) | HTR2CHTR2ACDK4CCND1LMNA | |
| SCHEMBL2947992 | 0.77 | KDM4E (0.46) | PLGPLAUMTNR1AMTNR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943220-A2 | NOVEL INDOLE-CONTAINING BETA AGONISTS, METHOD FOR PRODUCING THEM AND THEIR USE AS DRUGS | Boehringer Ingelheim International GmbH (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048841-A2 | NOVEL INDOLE-CONTAINING BETA AGONISTS, METHOD FOR PRODUCING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |