Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 5/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.46 |
| ▸ | AKT1 | P31749 | 11/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | AKT2 | P31751 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.38 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121024 | 1.00 | FPR1 (0.46) | FPR1FPR2AKT1SSTR4NTRK1 | |
| SCHEMBL146484 | 0.90 | KDM1A (0.40) | FPR1FPR2NTRK1 | |
| SCHEMBL146483 | 0.90 | KDM1A (0.40) | FPR1FPR2NTRK1 | |
| SCHEMBL146482 | 0.90 | KDM1A (0.40) | FPR1FPR2NTRK1 | |
| SCHEMBL13178100 | 0.88 | FPR1 (0.46) | FPR1FPR2AKT1SSTR4AKT2 | |
| SCHEMBL12891129 | 0.88 | FPR1 (0.46) | FPR1FPR2AKT1SSTR4AKT2 | |
| SCHEMBL121035 | 0.87 | SSTR4 (0.46) | FPR1FPR2SSTR4 | |
| SCHEMBL1721284 | 0.84 | FPR1 (0.47) | FPR1FPR2AKT1NTRK1AKT2 | |
| SCHEMBL12284238 | 0.83 | FPR1 (0.53) | FPR1FPR2NTRK1 | |
| SCHEMBL764675 | 0.83 | FPR1 (0.53) | FPR1FPR2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |