SCHEMBL121035

SCHEMBL121035

CC(C)(C)OC(=O)N[C@H]1CNCC[C@@H]1c1ccccc1F

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 8/20 0.46
FPR1 P21462 7/20 0.45
FPR2 P25090 4/20 0.45
KDM1A O60341 3/20 0.43
MAOB P27338 1/20 0.42
EPHX2 P34913 1/20 0.42
SSTR1 P30872 6/20 0.41
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458054 0.90 EPHX2 (0.44) SSTR4KDM1AMAOBEPHX2SSTR1
SCHEMBL14722720 0.90 EPHX2 (0.44) SSTR4KDM1AMAOBEPHX2SSTR1
SCHEMBL461792 0.87 FPR1 (0.46) SSTR4FPR1FPR2
SCHEMBL121024 0.87 FPR1 (0.46) SSTR4FPR1FPR2
SCHEMBL12891129 0.85 FPR1 (0.46) SSTR4FPR1FPR2KDM1A
SCHEMBL13178100 0.85 FPR1 (0.46) SSTR4FPR1FPR2KDM1A
SCHEMBL7826671 0.83 KDM1A (0.57) SSTR4FPR1FPR2KDM1AMAOB
SCHEMBL1721363 0.83 KDM1A (0.50) SSTR4FPR1FPR2KDM1ASSTR1
SCHEMBL458426 0.81 EPHX2 (0.40) SSTR4FPR1FPR2KDM1AMAOB
SCHEMBL19988381 0.78 FPR1 (0.62) FPR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120059014-A1 Compounds for the Treatment of Metabolic Disorders PROSIDION LIMITED (GB) 2012-03-08 US disclosed
US-20120059014-A1 Compounds for the Treatment of Metabolic Disorders PROSIDION LIMITED (GB) 2012-03-08 US disclosed
US-20120059014-A1 Compounds for the Treatment of Metabolic Disorders PROSIDION LIMITED (GB) 2012-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059014-A1 Compounds for the Treatment of Metabolic Disorders GPR119, FFAR2, GPBAR1 SSTR4 145/4885FPR1 717/4885FPR2 571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.