Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19765228 | 0.85 | ALDH1A1 (0.54) | ALDH1A1RAB9ANPC1TSHRTDP1 | |
| SCHEMBL5932420 | 0.84 | ALDH1A1 (0.55) | ALDH1A1RAB9ANPC1TSHRTDP1 | |
| SCHEMBL442437 | 0.84 | ALDH1A1 (0.52) | ALDH1A1RAB9ANPC1TSHRTDP1 | |
| SCHEMBL30163264 | 0.84 | ALDH1A1 (0.55) | ALDH1A1RAB9ANPC1TSHRTDP1 | |
| SCHEMBL1232755 | 0.84 | ALDH1A1 (0.45) | ALDH1A1RAB9ANPC1TSHRTDP1 | |
| SCHEMBL6523075 | 0.84 | ALDH1A1 (0.51) | ALDH1A1RAB9ANPC1TSHRTDP1 | |
| SCHEMBL30061341 | 0.83 | ALDH1A1 (0.44) | ALDH1A1RAB9ANPC1TSHRTDP1 | |
| SCHEMBL13069883 | 0.83 | ALDH1A1 (0.53) | ALDH1A1RAB9ANPC1TSHRTDP1 | |
| SCHEMBL27433027 | 0.83 | ALDH1A1 (0.50) | ALDH1A1RAB9ANPC1TSHRTDP1 | |
| SCHEMBL287344 | 0.83 | ALDH1A1 (0.57) | ALDH1A1RAB9ANPC1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946058-A | Preparation method of 3-isochromone | 上海试四化学品有限公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-1893766-A1 | CHEMOENZYMATIC PROCESS FOR THE SYNTHESIS OF ESCITALOPRAM | Adorkem Technology SpA (IT) | 2008-03-05 | — | — | EP | disclosed |
| US-20070161681-A1 | ETHER DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES | PFIZER INC. (US) | 2007-07-12 | — | — | US | disclosed |
| US-7183293-B2 | Ether derivatives useful as inhibitors of PDE4 isozymes | PFIZER INC. (US) | 2007-02-27 | — | — | US | disclosed |
| WO-2006136521-A1 | CHEMOENZYMATIC PROCESS FOR THE SYNTHESIS OF ESCITALOPRAM | ADORKEM TECHNOLOGY SPA (IT) | 2006-12-28 | — | — | WO | disclosed |
| EP-1733042-A1 | CHEMO-ENZYMATIC PROCESS FOR PREPARING ESCITALOPRAM | Adorkem Technology SpA (IT) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005098018-A1 | CHEMO-ENZYMATIC PROCESS FOR PREPARING ESCITALOPRAM | ADORKEM TECHNOLOGY SPA (IT) | 2005-10-20 | — | — | WO | disclosed |
| US-4091010-A | Process for the preparation of cyanohydrin esters | SUNTECH, INC. (US) | 1978-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161681-A1 | ETHER DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES | PDE4A, PDE4B, PDE4D | ALDH1A1 424/4885RAB9A 993/4885NPC1 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.