Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4618290 | 0.84 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9ATSHRCASP3 | |
| SCHEMBL17941764 | 0.84 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ATSHRCASP3 | |
| SCHEMBL5255523 | 0.82 | ALDH1A1 (0.65) | ALDH1A1RAB9AMAPTL3MBTL1CYP1A2 | |
| SCHEMBL1268572 | 0.79 | ALDH1A1 (0.37) | ALDH1A1NPC1RAB9ATSHRCASP3 | |
| SCHEMBL878375 | 0.79 | PPARG (0.58) | ALDH1A1NPC1RAB9ATSHRCASP3 | |
| SCHEMBL17729329 | 0.79 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9ATSHRCASP3 | |
| SCHEMBL7677777 | 0.77 | FFAR1 (0.47) | ALDH1A1TSHRL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL11580414 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTL3MBTL1CYP1A2 | |
| SCHEMBL7185506 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL7675499 | 0.76 | ALDH1A1 (0.57) | ALDH1A1RAB9AMAPTL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | MELINTA SUBSIDIARY CORP. (US) | 2024-06-04 | — | — | US | disclosed |
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| EP-4356736-A2 | SYNTHESIS OF BORONATE SALTS | Melinta Therapeutics, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-3604316-B1 | SYNTHESIS OF BORONATE SALTS | MELINTA THERAPEUTICS INC (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20200308197-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2020-10-01 | — | — | US | disclosed |
| EP-3704130-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | Melinta Therapeutics, Inc. (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10669292-B2 | Synthesis of boronate salts and uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| EP-3604316-A1 | SYNTHESIS OF BORONATE SALTS | Rempex Pharmaceuticals, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| US-20200031851-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2020-01-30 | — | — | US | disclosed |
| US-6503711-B1 | Nucleic acid biosensor diagnostics | KRULL ULRICH J (CA) | 2003-01-07 | — | — | US | disclosed |
| WO-2002083702-A1 | PROCESS FOR SELECTIVE N-ACYLATION OF PURINE NUCLEOSIDES | ISIS PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | disclosed |
| EP-1242459-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-09-25 | — | — | EP | disclosed |
| US-20020045167-A1 | Used for detecting incomplete deprotection of a synthetic oligonucleotide by immunoassay | VERI-Q, INC. | 2002-04-18 | — | — | US | disclosed |
| WO-2001049745-A9 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | UNIV NORTH CAROLINA STATE (US) | 2001-09-20 | — | — | WO | disclosed |
| WO-2001049745-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-07-12 | — | — | WO | disclosed |
| EP-0991777-A1 | NUCLEIC ACID BIOSENSOR DIAGNOSTICS | Krull, Ulrich J. (CA) | 2000-04-12 | — | — | EP | disclosed |
| US-6015886-A | ANTISENSE AGENTS WITH MODIFICATIONS INCLUDING P-ALKOXY AND 2'-O-METHYL GROUPS; NUCLEASE RESISTANT, ABILITY TO ACTIVATE BACTERIAL RIBONUCLEASE H, FORM STABLE DUPLEXES WITH RNA, AND HAVE STRONG HYDROPHOBICITY FOR EFFICIENT CELLULAR UPTAKE | CHEMGENES CORPORATION (US) | 2000-01-18 | — | — | US | disclosed |
| WO-1998058079-A1 | NUCLEIC ACID BIOSENSOR DIAGNOSTICS | KRULL ULRICH J (CA) | 1998-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031851-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | BTD, BCL6B, BRI3BP | ALDH1A1 3175/4885NPC1 680/4885RAB9A 1994/4885 |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | ADH5, ADH1A, ADH7 | ALDH1A1 69/4885NPC1 1287/4885RAB9A 3139/4885 |
| US-10669292-B2 | Synthesis of boronate salts and uses thereof | BTD, BCL6B, BRI3BP | ALDH1A1 3175/4885NPC1 680/4885RAB9A 1994/4885 |
| US-20200308197-A1 | SYNTHESIS OF BORONATE ESTER DERIVATIVES AND USES THEREOF | ADH5, ADH1A, ADH7 | ALDH1A1 69/4885NPC1 1287/4885RAB9A 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.