Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | IAPP | P10997 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | BID | P55957 | 3/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.30 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.30 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.30 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483096 | 0.79 | MTNR1A (0.41) | CTRCMTNR1AALOX5PTGS2LIPG | |
| SCHEMBL28222763 | 0.74 | LIPG (0.46) | MTNR1AALOX5PTGS2LIPGCYP1A1 | |
| SCHEMBL4618444 | 0.73 | AHR (0.41) | CYP1A1 | |
| SCHEMBL18153979 | 0.73 | LIPG (0.49) | MTNR1AALOX5PTGS2LIPGCYP1A1 | |
| SCHEMBL3105944 | 0.73 | AHR (0.33) | — | |
| SCHEMBL29432879 | 0.73 | LIPG (0.49) | MTNR1AALOX5PTGS2LIPGCYP1A1 | |
| SCHEMBL7054345 | 0.73 | LIPG (0.49) | MTNR1AALOX5PTGS2LIPGCYP1A1 | |
| SCHEMBL3104009 | 0.72 | AHR (0.53) | — | |
| SCHEMBL3106117 | 0.69 | AHR (0.33) | — | |
| SCHEMBL23891754 | 0.68 | MTNR1A (0.48) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945029-A2 | INHIBITORS OF ION CHANNELS | Icagen, Inc. (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056099-A2 | INHIBITORS OF ION CHANNELS | ICAGEN, INC. (US) | 2007-05-18 | — | — | WO | disclosed |