SCHEMBL4618532

SCHEMBL4618532

CCC(Br)(Br)c1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.54
ALDH1A1 P00352 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
CA2 P00918 4/20 0.39
CA12 O43570 2/20 0.39
CA14 Q9ULX7 2/20 0.39
HIF1A Q16665 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
GMNN O75496 1/20 0.39
EGFR P00533 1/20 0.39
LMNA P02545 1/20 0.39
FYN P06241 1/20 0.39
POLB P06746 1/20 0.39
CA3 P07451 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
MMP9 P14780 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2875372 0.83 TP53 (0.35) TSHRALDH1A1TDP1CA2GABRA1
SCHEMBL5587196 0.83 ALDH1A1 (0.44) TSHRALDH1A1TDP1CA2CA12
SCHEMBL4619728 0.83 TSHR (0.50) TSHRALDH1A1TDP1CA2CA12
SCHEMBL29372814 0.79 TSHR (0.56) TSHRALDH1A1TDP1CA2CA12
SCHEMBL505600 0.79 TSHR (0.56) TSHRALDH1A1TDP1CA2CA12
SCHEMBL6522579 0.79 TSHR (0.56) TSHRALDH1A1TDP1CA2CA12
SCHEMBL31276573 0.79 TSHR (0.56) TSHRALDH1A1TDP1CA2CA12
SCHEMBL980707 0.79 TSHR (0.56) TSHRALDH1A1TDP1CA2CA12
SCHEMBL9308101 0.77 TSHR (0.54) TSHRALDH1A1TDP1CA2CA12
SCHEMBL28430326 0.77 ALDH1A1 (0.60) TSHRALDH1A1TDP1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180327671-A1 FLAME RETARDANT LIQUID SOLUTION, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM ICL-IP AMERICA INC. 2018-11-15 US disclosed
EP-1893680-A1 FLAME RETARDANT COMPOSITION EXHIBITING SUPERIOR THERMAL STABILITY AND FLAME RETARDING PROPERTIES AND USE THEREOF ALBEMARLE CORPORATION (US) 2008-03-05 EP disclosed
US-20070018143-A1 Flame retardant composition exhibiting superior thermal stability and flame retarding properties and use thereof ALBEMARLE CORPORATION 2007-01-25 US disclosed
WO-2006132900-A1 FLAME RETARDANT COMPOSITION EXHIBITING SUPERIOR THERMAL STABILITY AND FLAME RETARDING PROPERTIES AND USE THEREOF ALBEMARLE CORPORATION (US) 2006-12-14 WO disclosed
EP-1627013-A2 STABILIZED FLAME RETARDANT ADDITIVES AND THEIR USE ALBEMARLE CORPORATION (US) 2006-02-22 EP disclosed
EP-1127917-B1 Flame-retardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-30 EP disclosed
WO-2004104098-A2 STABILIZED FLAME RETARDANT ADDITIVES AND THEIR USE ALBEMARLE CORPORATION (US) 2004-12-02 WO disclosed
US-20040229982-A1 Stabilized flame retardant additives and their use GOOSSENS DANIELLE F (BE) 2004-11-18 US disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 US disclosed
US-6296979-B1 ACOUSTICS FUJI XEROX CO., LTD. (JP) 2001-10-02 US disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 EP disclosed