SCHEMBL900597

SCHEMBL900597

[Ru]c1c(P(c2ccccc2)c2ccccc2)ccc2ccccc12.[c]1c(P(c2ccccc2)c2ccccc2)ccc2ccccc12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234550 0.82 CYP3A4 (0.42)
SCHEMBL356683 0.82 CYP3A4 (0.42)
SCHEMBL4619337 0.81 CYP3A4 (0.41)
SCHEMBL16180769 0.81 CYP3A4 (0.41)
SCHEMBL5330004 0.74 ESR1 (0.36)
SCHEMBL4744273 0.70 CYP3A4 (0.31)
SCHEMBL1443600 0.70 CYP2A6 (0.35)
SCHEMBL1460886 0.67 CYP2A6 (0.35)
SCHEMBL29350037 0.67 ALDH1A1 (0.44)
SCHEMBL29496111 0.67 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2621893-A1 PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB Pharma GmbH (DE) 2013-08-07 EP claimed
WO-2012041986-A1 PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB PHARMA GMBH (DE) 2012-04-05 WO claimed
EP-2621893-A1 PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB Pharma GmbH (DE) 2013-08-07 EP disclosed
EP-2531486-A2 NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES UCB Pharma GmbH (DE) 2012-12-12 EP disclosed
WO-2012041986-A1 PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB PHARMA GMBH (DE) 2012-04-05 WO disclosed
WO-2011095539-A2 NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES UCB PHARMA GMBH (DE) 2011-08-11 WO disclosed