Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.52 |
| ▸ | PTPRB | P23467 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | PTEN | P60484 | 1/20 | 0.51 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | GNA15 | P30679 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977902 | 0.83 | AKR1B1 (0.50) | FFAR1PPARDTDP1AKR1B1 | |
| SCHEMBL4644508 | 0.83 | SIRT2 (0.48) | — | |
| SCHEMBL7620631 | 0.81 | FFAR1 (0.56) | FFAR1KEAP1FFAR4PTPRBCDC25A | |
| SCHEMBL29085766 | 0.81 | FFAR1 (0.56) | FFAR1KEAP1FFAR4PTPRBCDC25A | |
| SCHEMBL346302 | 0.81 | FFAR1 (0.65) | FFAR1 | |
| SCHEMBL1205673 | 0.81 | FFAR1 (0.74) | FFAR1KEAP1FFAR4GNA15PTGER3 | |
| SCHEMBL1852100 | 0.80 | CYP4F2 (0.61) | TDP1 | |
| SCHEMBL70271 | 0.80 | KEAP1 (0.74) | FFAR1KEAP1FFAR4PTPRBCDC25A | |
| SCHEMBL5798172 | 0.79 | FFAR1 (0.62) | FFAR1KEAP1FFAR4 | |
| SCHEMBL1205628 | 0.79 | FFAR4 (0.71) | FFAR1KEAP1FFAR4PTPRBCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039882-A1 | A COMBINATION OF NIACIN AND A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST | SANOFI-AVENTIS U.S. LLC (US) | 2008-04-03 | — | — | WO | disclosed |
| EP-1891019-A2 | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006044732-A2 | 2, 6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2006-04-27 | — | — | WO | disclosed |